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Be sure to read Geoff Pain's articles the toxicity of DSMO https://geoffpain.substack.com/p/dmso-gentoxicity-via-z-dna and of the closely related Methysulfonylmethane (MSM) https://geoffpain.substack.com/p/methyl-sulfonyl-methane-msm-adverse which, according to a 1975 reference https://pubmed.ncbi.nlm.nih.gov/1055534/ cited by https://en.wikipedia.org/wiki/Methylsulfonylmethane, is a metabolite of DSMO.

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Paywalled. I would be interested to hear the strength and rigour of Geoff's arguments though; the work by A Midwestern Doctor appears very well researched and no such concerns have been raised in it, far as I'm aware...

PS that paper appears to simply relate to the ability of DMSO (which is a solvent) and related metabolites to bring other compounds into the body - which can be good or bad, depending upon the compound.

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